Growth kinetics of Kaposi's sarcoma

Kaposis sarcoma in a Nairobi hospital.

BACKGROUND Kaposi's sarcoma (KS) is associated epidemiologically with HIV infection and a number of countries have reported a dramatic increase in the incidence of KS with the advent of AIDS. Although AIDS is prevalent in Kenya, no studies on the impact of AIDS on the pattern of KS has been carried out. OBJECTIVE To determine any changes in the pattern of KS that might have occurred since the...

Heterologous Growth of Sarcoma

Ehrlich was the first to demonstrate, by his famous “zig-zag― (i.e., mouse to rat to mouse, etc.) experiment, that the Ehrlich mouse sarcoma can grow in rats (4). Russell showed that a mouse tumor designated as “@7― multiplied and survived in rats 9 days before regressing (1@). Murphy demonstrated that mammalian tumors may be grown in the developing chick embryo (7). Mur phy and Rous re...

The kinetics of growth.

Kinetics of prion growth.

We study the kinetics of prion fibril growth, described by the nucleated polymerization model analytically and by means of numerical experiments. The elementary processes of prion fibril formation lead us to a set of differential equations for the number of fibrils, their total mass, and the number of prion monomers. In difference to previous studies we analyze this set by explicitly taking int...

Kinetics of Kaposi's sarcoma-associated herpesvirus gene expression.

Herpesvirus gene expression can be classified into four distinct kinetic stages: latent, immediate early, early, and late. Here we characterize the kinetic class of a group of 16 Kaposi's sarcoma-associated herpesvirus (KSHV)/human herpesvirus 8 genes in a cultured primary effusion cell line and examine the expression of a subset of these genes in KS biopsies. Expression of two latent genes, LA...